Private & Confidential
Seqera × Anthropic

The Workflow Engine
for AI in Life Sciences

Nextflow is the most widely adopted workflow engine in life sciences. Claude is the most capable AI for scientific reasoning. Together, it closes the loop on AI-assisted discovery and execution.

February 19, 2026
AstraZeneca GSK Pfizer Roche AbbVie Moderna
5,000+
Open Source contributors
2.5M+
Monthly runs
130+
Life Sciences customers
13/20
Top Biopharma
The Problem
Bioinformatics workflows are extraordinarily complex

A multi-omics drug discovery pipeline can involve sequencing data generation, quality control, variant calling across thousands of samples, gene expression analysis, protein structure prediction, pathway enrichment, and integration with clinical trial data for machine learning. Each step has dozens of configuration parameters, and scientists spend weeks developing and troubleshooting when workflows fail or produce unexpected results.

Scale
Nextflow adoption is accelerating

Nextflow, created by the founders of Seqera, is the solution to this complexity. It has become the dominant technology for bioinformatics and computational biology. Daily workflow runs have grown from ~20K in early 2024 to regularly exceeding 100K.

Daily runs 14-day avg AI era
Source: Nextflow telemetry
What exists today
Anthropic's Nextflow Skill

Anthropic recently launched the Nextflow Development Skill as part of the Claude for Life Sciences initiative. It enables bench scientists to run omics analyses without specialized bioinformatics training, but is currently limited to local execution of a subset of nf-core pipelines. The next step is agentic orchestration at enterprise scale, on any pipeline and with full traceability.

BioPipelineBench assesses AI's ability to execute bioinformatics workflows spanning targeted and long-read sequence analysis, metagenome assembly, and chromatin profiling. The rate of improvement signals practical viability.

Source: Anthropic BioPipelineBench
The opportunity
Why this matters for Anthropic
$2T+
Market in motion
Life sciences is primed for AI adoption. The AI-to-execution bridge will enable an extraordinary era in drug development, diagnostics and result in vast benefits to humanity.
100+
Community pipelines
Production-grade pipelines maintained by 5,000+ contributors. The ready-made library of executable scientific code for AI agents to orchestrate and widely used across biopharma.
#1
Standard in Life Sciences
Every major competitor (AWS HealthOmics, DNAnexus, Velsera, LatchBio) runs Nextflow under the hood. Partnering with Seqera locks in the infrastructure layer.
GxP
Regulated environments
Pharma deployments require governance, audit trails, and reproducibility. Seqera provides the guardrails that only an enterprise platform can deliver.
Momentum
Transforming Bioinformatics with Claude

Seqera is now rewriting the fundamental pipelines for biology. With Claude Opus 4.6, we developed RustQC, a quality control pipeline that was rebuilt from the ground up. We were able to achieve a remarkable 21x performance improvement.

RustQC Benchmark Results
Agents
Agent-driven pipeline optimization

Seqera is using AI agents to massively parallelize workflow optimizations.

Systematic exploration
AI agents evaluate thousands of parameter combinations across tools, references, and thresholds to find optimal configurations for each dataset.
Parallel execution
Nextflow's native parallelism combined with Claude's reasoning enables simultaneous optimization across pipeline stages at enterprise scale.
Quality-driven iteration
Agents compare outputs against gold-standard references, iterating on parameters until results meet or exceed expert-level benchmarks.
BioML training data
Optimized pipeline outputs become high-quality training data for biological ML models, creating a flywheel between workflow execution and AI improvement.
Seqera x Anthropic

By joining Seqera's expertise in Life Sciences with Anthropic's scientific reasoning, we can radically change the trajectory of human health.

"We can make 100 years of progress in areas like biology in five or ten years"— Dario Amodei
Next steps
Proposed next steps
1
Introduction
Connect Seqera leadership with Anthropic's Life Sciences team.
2
Technical deep-dive
Joint session to explore skills and integration architecture.
3
Validate on BioPipelineBench
Run Seqera's Claude-powered agent against BioPipelineBench.